Helena Gylling Selected Research

Cholesterol

4/2021	Obesity Does Not Interfere with the Cholesterol-Lowering Effect of Plant Stanol Ester Consumption (as Part of a Heart-Healthy Diet).
1/2021	Intestinal cholesterol and phytosterol absorption and the risk of coronary artery disease.
1/2021	Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2-mediated mechanism.
1/2020	HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD.
1/2019	Altered Bile Transporter Expression and Cholesterol Metabolism in Children With Cholesterol and Pigment Gallstones.
12/2018	Serum noncholesterol sterols in Alzheimer's disease: the Helsinki Businessmen Study.
11/2018	Serum non-cholesterol sterols and cholesterol metabolism in childhood and adolescence.
10/2018	Progress and perspectives in plant sterol and plant stanol research.
9/2018	Genetic polymorphism of sterol transporters in children with future gallstones.
1/2018	Determining the mechanisms of dietary turnip rapeseed oil on cholesterol metabolism in men with metabolic syndrome.

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Helena Gylling Research Topics

Disease

22	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 09/2002
19	Obesity 04/2021 - 11/2005
16	Insulin Resistance 01/2018 - 05/2002
15	Hypercholesterolemia 01/2021 - 01/2002
15	Inflammation (Inflammations) 01/2020 - 07/2007
14	Type 2 Diabetes Mellitus (MODY) 01/2018 - 02/2002
14	Weight Loss (Weight Reduction) 01/2017 - 02/2002
12	Cardiovascular Diseases (Cardiovascular Disease) 08/2020 - 01/2004
11	Atherosclerosis 01/2020 - 01/2001
10	Non-alcoholic Fatty Liver Disease 01/2020 - 01/2011
10	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 08/2016 - 07/2002
10	Body Weight (Weight, Body) 09/2015 - 02/2002
8	Overweight 04/2021 - 09/2007
7	Coronary Artery Disease (Coronary Atherosclerosis) 10/2022 - 01/2001
7	Liver Diseases (Liver Disease) 08/2016 - 02/2006
7	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2011 - 01/2004
7	Coronary Disease (Coronary Heart Disease) 01/2009 - 02/2003
5	Cholelithiasis 01/2019 - 06/2015
4	Gallstones (Gallstone) 01/2019 - 06/2015
4	Fatty Liver 01/2018 - 01/2011
4	Hyperinsulinism (Hyperinsulinemia) 01/2018 - 03/2004
4	Intestinal Failure 01/2017 - 10/2011
4	Cholestasis 08/2016 - 02/2006
3	Hypoxia (Hypoxemia) 01/2020 - 01/2010
3	Hyperglycemia 07/2017 - 11/2012
3	Fibrosis (Cirrhosis) 12/2014 - 02/2006
3	Sitosterolemia 01/2009 - 09/2004
2	Alzheimer Disease (Alzheimer's Disease) 12/2018 - 02/2014
2	Dyslipidemias (Dyslipidemia) 11/2018 - 01/2016
2	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2018 - 12/2014
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2017 - 08/2016
2	Atherosclerotic Plaque (Atheroma) 04/2016 - 06/2005
2	Aortic Valve Stenosis (Aortic Stenosis) 12/2015 - 07/2008
2	Alcoholic Fatty Liver 07/2015 - 03/2012
2	Glucose Intolerance 08/2010 - 08/2007
2	Short Bowel Syndrome 08/2010 - 08/2008
2	Morbid Obesity 06/2010 - 01/2004
2	Necrosis 06/2010 - 04/2008
2	Abdominal Obesity 06/2007 - 07/2006
2	Hyperlipidemias (Hyperlipidemia) 04/2006 - 09/2002
1	Frailty 12/2018

Drug/Important Bio-Agent (IBA)

75	CholesterolIBA 04/2021 - 01/2001
38	Phytosterols (Plant Sterols)IBA 10/2022 - 02/2002
35	SterolsIBA 12/2018 - 02/2002
18	LDL CholesterolIBA 04/2021 - 07/2002
17	Glucose (Dextrose)FDA LinkGeneric 12/2018 - 02/2002
17	Cholestanol (Coprostanol)IBA 01/2017 - 02/2002
16	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 09/2002
15	LipidsIBA 12/2018 - 01/2003
14	EstersIBA 08/2020 - 03/2003
13	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2004
12	oxidized low density lipoproteinIBA 01/2020 - 04/2003
11	Lipoproteins (Lipoprotein)IBA 12/2014 - 04/2003
10	lathosterolIBA 12/2018 - 01/2004
10	Insulin (Novolin)FDA Link 03/2014 - 02/2002
9	Triglycerides (Triacylglycerol)IBA 01/2018 - 02/2002
8	campesterolIBA 09/2018 - 04/2004
8	SqualeneIBA 01/2018 - 04/2003
7	LDL Lipoproteins (beta Lipoproteins)IBA 04/2021 - 07/2002
7	Messenger RNA (mRNA)IBA 01/2018 - 02/2008
6	plant stanol esterIBA 04/2021 - 02/2003
6	DesmosterolIBA 12/2018 - 12/2006
5	gamma-sitosterol (beta-sitosterol)IBA 01/2018 - 09/2007
5	LDL Receptors (LDL Receptor)IBA 08/2016 - 05/2004
5	HDL CholesterolIBA 09/2015 - 09/2002
4	Bile Acids and Salts (Bile Acids)IBA 01/2019 - 09/2013
4	Fatty Acids (Saturated Fatty Acids)IBA 07/2017 - 01/2001
4	Interleukin-6 (Interleukin 6)IBA 10/2012 - 08/2007
4	C-Reactive ProteinIBA 10/2012 - 04/2006
3	EnzymesIBA 10/2011 - 08/2008
2	Rapeseed OilIBA 01/2018 - 07/2006
2	MonosaccharidesIBA 01/2018 - 10/2012
2	StigmasterolIBA 01/2017 - 10/2014
2	Ezetimibe (Zetia)FDA Link 08/2016 - 11/2005
2	MargarineIBA 12/2015 - 03/2006
2	Phenobarbital (Luminal)FDA Link 11/2013 - 09/2013
2	CarbohydratesIBA 10/2012 - 12/2006
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 03/2012 - 02/2008
2	CytokinesIBA 06/2010 - 02/2008
2	Interleukin-1beta (Interleukin 1 beta)IBA 06/2010 - 04/2008
2	AdipokinesIBA 02/2008 - 08/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2008 - 08/2007
2	Simvastatin (Zocor)FDA LinkGeneric 04/2007 - 02/2003
2	IDL Lipoproteins (Lipoprotein, IDL)IBA 01/2004 - 04/2003
2	Sex Hormone-Binding GlobulinIBA 09/2002 - 02/2002
1	SteroidsIBA 04/2021
1	Pharmaceutical PreparationsIBA 01/2021
1	Methionine (L-Methionine)FDA Link 01/2020
1	FructoseIBA 01/2020
1	Oxygen (Dioxygen)IBA 01/2020
1	Choline (Choline Chloride)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2019
1	Apolipoproteins E (ApoE)IBA 12/2018
1	CeramidesIBA 01/2018

Therapy/Procedure

5	Parenteral Nutrition 10/2014 - 08/2008
4	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2017 - 01/2004
4	Therapeutics 02/2014 - 01/2002
3	Caloric Restriction 10/2016 - 02/2014
3	Liver Transplantation 08/2016 - 02/2006
1	Diet Therapy (Therapy, Diet) 04/2021